Cell–Matrix De-Adhesion Dynamics Reflect Contractile Mechanics
نویسندگان
چکیده
منابع مشابه
Cell–Matrix De-Adhesion Dynamics Reflect Contractile Mechanics
Measurement of the mechanical properties of single cells is of increasing interest both from a fundamental cell biological perspective and in the context of disease diagnostics. In this study, we show that tracking cell shape dynamics during trypsin-induced de-adhesion can serve as a simple but extremely useful tool for probing the contractility of adherent cells. When treated with trypsin, bot...
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By pressure-controlled surface contact area, reversible adhesion can be achieved with strengths tunable by 3 orders of magnitude. This capability facilitates robust transfer printing of active materials and devices onto any surface for the development of stretchable and/or curvilinear electronics. The most important parameter in designing the surfaces of stamps for this process is the height of...
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Tissue cells generally pull on their matrix attachments and balance a quasi-static contractility against adequate adhesion, but any correlation with and/or influence on phenotype are not yet understood. Here, we begin to demonstrate how differentiation state couples to actomyosin-based contractility through adhesion and substrate compliance. Myotubes are differentiated from myoblasts on collage...
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ژورنال
عنوان ژورنال: Cellular and Molecular Bioengineering
سال: 2009
ISSN: 1865-5025,1865-5033
DOI: 10.1007/s12195-009-0057-7